Exploration into conolidine has triggered discovery of the opioid receptor in the human body identified as ACKR3/CXCR7. ACKR3 is apparently one of the most sought after focus on for conolidine, which also disregards another four classical opioid receptors(3).Corydalis is definitely the genus of the perennial flowering plant in the poppy family with

Conolidine is actually a natural alkaloid derived from the bark with the tropical shrub Tabernaemontana divaricata, also called crepe jasmine. This shrub was customarily Utilized in Chinese, Ayurvedic, and Thai drugs, and is also well-known for its strong ache-relieving properties.Szpakowska et al. also researched conolidone and its action to the A